Clinical Care Guidelines


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Prevention
Screening
Treatment


Prevention


Sexually Transmitted Infections: Behavioral Counseling
U.S. Preventative Services Task Force, 2014
These recommendations address intensive behavioral counseling to prevent STIs for both sexually active and non-sexually active adolescents.

HIV Prevention in Clinical Care Settings
International Antiviral Society–USA Panel, 2014
This publication provides current recommendations for the prevention of HIV infection in adults and adolescents for integration in clinical care settings. Data support the integration of biomedical and behavioral approaches for prevention of HIV infection in clinical care settings.

Clinical Practice Guidelines for PrEP
U.S. Public Health Service, 2014
On May 14, 2014, the U.S. Public Health Service released the first comprehensive clinical practice guidelines for PrEP. The guidelines were developed by a federal inter-agency working group led by CDC, and reflect input from providers, HIV patients, partners, and affected communities. (See pages 42–43 on use of PrEP for youth under the age of 18.)

Screening


Screening for Nonviral Sexually Transmitted Infections in Adolescents and Young Adults
American Academy of Pediatrics and Society for Adolescent Health and Medicine, 2014
Prevalence rates of many STIs are highest among adolescents. This policy statement specifically focuses on these curable, nonviral STIs and reviews the evidence for nonviral STI screening in adolescents, communicates the value of screening, and outlines recommendations for routine nonviral STI screening of adolescents.

Screening for Chlamydia
U.S. Preventative Services Task Force, 2014
These recommendations address screening for chlamydial infection. Recommendations cover sexually active youth.

Screening for Gonorrhea
U.S. Preventative Services Task Force, 2014
These recommendations address screening for gonorrhea in male and female adolescents and young adults.

Screening for Syphilis Infection
U.S. Preventative Services Task Force, 2004
These recommendations address screening for syphilis in persons who are at increased risk for infection. (Note: These recommendations are in the process of being updated.)

Screening for Hepatitis B Virus Infection in Nonpregnant Adolescents and Adults
U.S. Preventative Services Task Force, 2014
These recommendations address screening for hepatitis B virus infection in adolescents and adults.  

Screening for Genital Herpes
U.S. Preventative Services Task Force, 2005
These recommendations address screening for herpes simplex virus in adolescents and adults.

Screening for HIV
U.S. Preventative Services Task Force, April 2013
These recommendations address screening for HIV infections in adolescents and adults as well as pregnant women.

Adolescents and HIV Infection: The Pediatrician’s Role in Promoting Routine Testing
American Academy of Pediatrics, 2011
This policy statement affirms the key role that pediatricians can play in preventing and controlling HIV infection by promoting risk-reduction counseling and offering routine HIV testing to adolescent and young adult patients. This statement addresses many of the real and perceived barriers that pediatricians face in promoting routine HIV testing for their patients.



Treatment


2015 STD Treatment Guidelines
Centers for Disease Control and Prevention, 2015
These guidelines for the treatment of persons who have or are at risk for STDs were updated by the CDC and discuss alternative treatment regimens for Neisseria gonorrhoeae; the use of nucleic acid amplification tests for the diagnosis of trichomoniasis; alternative treatment options for genital warts; the role of Mycoplasma genitalium in urethritis/cervicitis and treatment-related implications; updated HPV vaccine recommendations and counseling messages; the management of persons who are transgender; annual testing for hepatitis C in persons with HIV infection; updated recommendations for diagnostic evaluation of urethritis; and retesting to detect repeat infection. 

Changes in the 2010 STD Treatment Guidelines: What Adolescent Healthcare Providers Should Know
Society for Adolescent Health and Medicine
This page highlights changes in the CDC’s 2010 STD Treatment Guidelines that are important for clinicians who care for adolescents.

Expedited Partner Therapy in the Management of Gonorrhea and Chlamydia by Obstetrician-Gynecologists
American College of Obstetricians and Gynecologists, 2011
This Committee Opinion (No. 506) supports expedited partner therapy (EPT) in the management of gonorrhea and chlamydial infections when the partner is unlikely or unable to otherwise receive in-person evaluation and appropriate treatment. Clinicians are encouraged to be aware of state laws regarding EPT and advocate its legality.

Expedited Partner Therapy for Adolescents Diagnosed with Chlamydia or Gonorrhea: A Position Paper of the Society for Adolescent Medicine
Society for Adolescent Health and Medicine, 2009
Chlamydia and gonorrhea present substantial public health challenges among adolescents. This position paper provides recommendations for the use of expedited partner therapy by providers who care for adolescents.

Vaginitis
American College of Obstetricians and Gynecologists, 2006
This practice bulletin (No. 72) aids practitioners in making decisions about appropriate obstetric and gynecologic care for women and pediatric or adolescent girls with vulvovaginal symptoms such as itching, burning, irritation, and abnormal discharge, and provides information about the diagnosis and treatment of vaginitis.

Diagnosis and Management of Hepatitis C Infection in Infants, Children, and Adolescents
North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, 2012
These guidelines provide details on the epidemiology and natural history of hepatitis C virus (HCV) infection in children, and the diagnostic workup, monitoring, and treatment of HCV.

Gynecologic Herpes Simplex Virus Infections
American College of Obstetricians and Gynecologists, 2004
This practice bulletin (No. 57) aids practitioners in making decisions about appropriate obstetric and gynecologic care for women and adolescent girls with genital herpes simplex type 1 or type 2 infection. In addition, it reviews recent advances in diagnostic methods and therapeutic options in the management of genital herpes.

HIV Infection and AIDS in Adolescents: An Update of the Position of the Society for Adolescent Medicine
Society for Adolescent Health and Medicine, 2006
This position statement acknowledges that despite great progress in our scientific understanding of the virus and in the diagnosis and treatment of people living with HIV, great challenges remain for those working to prevent HIV/AIDS in adolescents and young adults and to provide treatment and care and support for those who already are infected.

Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents
U.S. Department of Health and Human Services, AIDSinfo.gov, 2014
These guidelines provide HIV care practitioners with recommendations based on current knowledge of antiretroviral (ARV) drugs used to treat adults and adolescents with HIV infection in the U.S. and generally represent the state of knowledge regarding the use of ARV agents.  

Antiretroviral Therapy (ART) for HIV Infection in Adults and Adolescents
World Health Organization, 2010
The guidelines identify the most potent, effective and feasible first-line, second-line, and subsequent treatment regimens, applicable to the majority of populations, the optimal timing of ART initiation and improved criteria for ART switching, and introduce the concept of third-line antiretroviral regimens.

HIV Post-Exposure Prophylaxis for Children Beyond the Perinatal Period
New York State Department of Health, 2010
The guidelines help medical providers identify and treat pediatric patients with potential HIV exposures and cover children beyond the perinatal period, including adolescents older than 13 years old.

Reproductive Health Care for Adolescents with Human Immunodeficiency Virus
American College of Obstetricians and Gynecologists, 2013
This Committee Opinion (No. 572) recognizes adolescent-focused care as critical to identifying and reducing at-risk behavior, comorbidities, and partner transmission. Optimal medical and reproductive health care, both now and in the future, with an adolescent-focused approach, are important for HIV-infected adolescents.


The goal of the AHRQ-funded project, Youth Providers 2.0 (YP2.0), is to improve the use of evidence-based practices among health care providers caring for adolescents and young adults. To accomplish this goal, SAHM will engage in a number of activities using new media to improve the dissemination of patient-centered outcomes research (PCOR) to health professionals.
 

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